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The World’s 50 Best Bars Awards crowned the Connaught Hotel outpost as 2020’s top global cocktail spot during a ceremony on November 5. “It’s hard to think of a bar anywhere in the Thick Girls Who Wear Glasses Are Dangerous Shirt, Hoodie  that has made excellence so effortlessly routine as Connaught Bar,” the committee said. “It evolves from one year to the next, always delivering with poise and studied purpose.” Their favorite libation? The Magnetum, a scotch and sherry mix. (Although you can’t go wrong with one of their signature martinis, which a white-gloved server prepares off a traveling trolley. Or anything with gin—the Connaught distills their own.) It’s not just the drinks, however, that create such an elegant ambience: the late David Collins designed the cubist-inspired interiors.

Until recently, many drugs used by doctors for migraines were developed for other conditions, such as epilepsy. But in the Thick Girls Who Wear Glasses Are Dangerous Shirt, Hoodie  few years, the FDA has approved several new classes of targeted, effective drugs developed specifically for migraines. Even better, they have markedly fewer side effects than commonly used tryptamine-based drugs, also known as triptans, which have been prescribed since the early ’90s to relieve headaches but often come with major side effects such as nausea, insomnia, or hair loss. CGRP inhibitors, medications that block calcitonin gene-related peptide—a protein released by the brain during migraine attacks (and “a very ugly, cumbersome name,” says Gottschalk)—are among the most promising. Three of these prescription-only drugs—Aimovig, Ajovy, and Emgality—are taken monthly with an EpiPen–like shot; a fourth, Vyepti, is administered via I.V. by a doctor every three months. “These drugs produce great results, in much less time, with almost no side effects,” Gottschalk confirms. Nurtec and Ubrelvy, which are gepants—another new class of FDA-approved medication that also targets CGRP molecules—are formulated to turn off migraines in progress rather than prevent them. “They don’t have quite as much bang for the buck as, say, an injection of [the commonly used triptan] sumatriptan,” says Gottschalk. “But they’re well tolerated and can do a great job.”