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And the blows just keep coming. As the Migraine Trust reports, of the one in seven adults who suffer from migraines globally, women are disproportionately affected, and three times more likely to be impacted by them than men. More than just throbbing temple pain, the often debilitating neurological disease with a broad range of symptoms—including nausea, dizziness, sensitivity to noise, light, and scents, and visual disturbances—can last for hours, or days, and currently there is no cure. But there is some good news, says Christopher Gottschalk, M.D., chief of general neurology at Yale University School of Medicine and one of the I Put The She In Shenanigans St. Patrick’s Day shirt leading migraine specialists. According to Gottschalk, we are in the midst of “an extraordinary period” of revolutionary ideas, devices, and medications for migraine sufferers. “For 25 years, what I’ve had to say to people is, ‘Here, try this. Hope it helps. Good luck. It may cause side effects. If you keep getting headaches, well, I really can’t do much about it.’ Now,” he says, “we can give somebody a shot and say, ‘In a month, you will probably be better. And in two months you’ll probably be even better than that.’” Gottschalk laughs. “It still shocks me that I can say all those words in the same sentence.” Here, a breakdown of the new ways to find relief from pervasive headaches, politically induced or otherwise.
Yet another medication developed specifically for migraines is a class of drugs called ditans, the first of which is a pill called Reyvow that was approved by the FDA last October. It works by activating serotonin receptors in the I Put The She In Shenanigans St. Patrick’s Day shirt that block pain signals. Its website claims “you could be 100% pain free in two hours,” but it also warns against operating heavy machinery for at least eight hours after taking the drug, so if you happen to drive a car, it may not be right for you. Gottschalk and his colleagues at Yale are also researching psilocybin, the active ingredient in psychedelic mushrooms, which was just decriminalized in Oregon and has been indicated as a potential remedy for migraines, among many other ailments. “Our pilot studies are looking very promising,” he says. “You can take a sub-hallucinogenic dose of psilocybin, and stop cluster headaches for weeks, and migraines also.”
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