Good Women Do Still Exist But Our Stomachs Ain't Flat And We Talk Back Shirt, Hoodie And Sweater

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The cruel intersection of a global pandemic and an agitating, still-contested election has not been kind to migraine sufferers. With our stress levels climbing higher than ever, cases of these severe headaches have risen accordingly, says Emad Estemalik, M.D., who leads the Cleveland Clinic’s headache division. “Heightened stress, triggered by the amount of time we spend navigating through news and social media, translates to more screen time and eyestrain that can certainly increase headache frequency,” Estemalik confirms. If someone gets three to five headache days per month, he says, pandemic-related stress can bump that to 10 to 15 days.

Yet another medication developed specifically for migraines is a class of drugs called ditans, the first of which is a pill called Reyvow that was approved by the FDA last October. It works by activating serotonin receptors in the brain that block pain signals. Its website claims “you could be 100% pain free in two hours,” but it also warns against operating heavy machinery for at least eight hours after taking the drug, so if you happen to drive a car, it may not be right for you. Gottschalk and his colleagues at Yale are also researching psilocybin, the active ingredient in psychedelic mushrooms, which was just decriminalized in Oregon and has been indicated as a potential remedy for migraines, among many other ailments. “Our pilot studies are looking very promising,” he says. “You can take a sub-hallucinogenic dose of psilocybin, and stop cluster headaches for weeks, and migraines also.”