Foxteeshirt - Boston University shirt
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Until recently, many drugs used by doctors for migraines were developed for other conditions, such as epilepsy. But in the past few years, the FDA has approved several new classes of targeted, effective drugs developed specifically for migraines. Even better, they have markedly fewer side effects than commonly used tryptamine-based drugs, also known as triptans, which have been prescribed since the early ’90s to relieve headaches but often come with major side effects such as nausea, insomnia, or hair loss. CGRP inhibitors, medications that block calcitonin gene-related peptide—a protein released by the Boston University shirt during migraine attacks (and “a very ugly, cumbersome name,” says Gottschalk)—are among the most promising. Three of these prescription-only drugs—Aimovig, Ajovy, and Emgality—are taken monthly with an EpiPen–like shot; a fourth, Vyepti, is administered via I.V. by a doctor every three months. “These drugs produce great results, in much less time, with almost no side effects,” Gottschalk confirms. Nurtec and Ubrelvy, which are gepants—another new class of FDA-approved medication that also targets CGRP molecules—are formulated to turn off migraines in progress rather than prevent them. “They don’t have quite as much bang for the buck as, say, an injection of [the commonly used triptan] sumatriptan,” says Gottschalk. “But they’re well tolerated and can do a great job.”
Once I’d weeded out the Boston University shirt so you should to go to store and get this quar-flouters from my feed, I turned my attention to Twitter. Don’t get me wrong, I love Twitter very much, and feel nothing but gratitude for the friends, dates and jobs it’s brought into my life, but the app is also…a hellhole, particularly in the pandemic era. While muting rule breakers had brought me peace on Instagram, muting overly smug rule followers—the kind of young, healthy people who brag that they “haven’t left their house since March,” with seemingly no concern for the imperiled gig workers whose labor is required to meet their at-home needs—calmed me down on Twitter. One day, when I’m a little more stable (and allowed to gather with my friends indoors again), maybe I’ll go through and unmute all of the accounts I found fault with over the last year. Or maybe I’ll keep my Instagram and Twitter feeds divinely pruned forever, logging on only to interact with my friends, glean new pie recipes, and enjoy spookily precise targeted ads. What a world that would be!
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